STRATEGIES TO INCREASE RESECTED LIVER METASTASES IN PATIENTS WITH COLORECTAL TUMORS Estratégias para aumentar a ressecabilidade em pacientes com metástases hepáticas de tumores colorretais

نویسندگان

  • Marcos Vinicius PERINI
  • Fabricio Ferreira COELHO
  • Fabio Ferrari MAKDISSI
  • Renato Miccelli LUPINACCI
  • Marcel Autran MACHADO
  • Paulo HERMAN
چکیده

HEADINGS Partial hepatectomy. Hepatic metastases. Colorectal cancer. Radiofrequency. Embolization. ABSTRACT – Introduction: Nowadays, liver resections can be performed with acceptable morbi-mortality rates. In specialized centers, mortality as low as 1% can be achieved, even with the advent of new hepatotoxic chemotherapy regimens. In order to reduce morbidity and mortality, newer strategies can be undertaken, such as portal vein embolization, radiofrequency ablation techniques, re-hepatectomies, major vascular resections and two stages hepatectomies. Method Literature review was conducted on sites search PubMed, BIREME, SciELO, with the headings “partial hepatectomy, hepatic metastases, colorectal cancer, radiofrequency and embolization”. Were selected mainly studies with the application of techniques and surgical procedures in the treatment of liver metastasis. Conclusion Survival rates as good as 50% in 5y can be achieved in selected cases when a multidisciplinary team is involved. Better surgical techniques, with parenchimal sparing strategies and the advent of neoadjuvant chemotherapy can turn unresectable liver lesions to resectable and increase survival rates. ABCDDV/820

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تاریخ انتشار 2012